1H-Pyrazolo[3,4-b]pyridin-5-ylamine HCl - Names and Identifiers
1H-Pyrazolo[3,4-b]pyridin-5-ylamine HCl - Physico-chemical Properties
Molecular Formula | C6H6N4
|
Molar Mass | 134.14 |
Density | 1.480±0.06 g/cm3(Predicted) |
Boling Point | 388.3±22.0 °C(Predicted) |
pKa | 10.43±0.40(Predicted) |
Storage Condition | Keep in dark place,Inert atmosphere,Room temperature |
1H-Pyrazolo[3,4-b]pyridin-5-ylamine HCl - Upstream Downstream Industry
1H-Pyrazolo[3,4-b]pyridin-5-ylamine HCl - Introduction
1H-PYRAZOLO [3,4-b] PYRIDIN-5-AMINE(1H-PYRAZOLO [3,4-b] PYRIDIN-5-AMINE) is an organic compound with the chemical formula C8H7N5. It has a white or light yellow solid state.
Nature:
-Appearance: White or light yellow solid
-Molecular weight: 173.18g/mol
-Melting Point: about 177-182 ° C
-Boiling Point: Not Applicable
-Solubility: Slightly soluble in water, soluble in ethanol, dichloromethane and acidic solvents
- pH: Neutral
Use:
1H-PYRAZOLO [3,4-b] PYRIDIN-5-AMINE is an important intermediate compound, often used in organic synthesis. It can be used to synthesize various bioactive compounds and drugs.
Method:
1H-PYRAZOLO [3,4-b] PYRIDIN-5-AMINE has many preparation methods, the following is one of the commonly used methods:
First, 1-phenylpyrazol-4-one was taken as a starting material. This is reacted with ammonia gas to give 1H-pyrazolo [3,4-b] pyridin -4-amine. Then, this was subjected to a chlorination substitution reaction, and the reaction was carried out using thionyl chloride as a reactant under appropriate conditions to obtain the target product, 1H-PYRAZOLO [3,4-b] pyridin-5-amine.
Safety Information:
The specific national safety data of 1H-PYRAZOLO [3,4-b] PYRIDIN-5-AMINE may vary in different databases, so it is recommended to consult the relevant safety data sheet before use. Generally speaking, it is usually a stable and operable compound, but the following matters still need to be paid attention:
-Avoid contact with skin and eyes and wear appropriate protective equipment if necessary
-Avoid inhalation or ingestion and operate in a well-ventilated place
-Keep it in a closed container when storing
-Follow Good Laboratory Practices and safe operating procedures during use and handling
Last Update:2024-04-09 21:01:54